top of page

A pathogenic role for IL-10 signalling in capillary stalling and cognitive impairment in type 1 diabetes

Nature Metabolism

Sorabh Sharma, Manjinder Cheema, Patrick Reeson, Kelly A. Tennant, Roobina Boghozian, Ana Paula Cota, Tara P. Brosschot, Rachael D. Fitzpatrick, Jakob Körbelin, Lisa A. Reynolds, and Craig E. Brown

Angiogenesis in the mature mouse cortex is governed in a regional and Notch1 dependent manner.

Cell Reports

Alejandra Raudales, Sorabh Sharma, Ben Schager, Dominique Hancock, Patrick Reeson, Manjinder Cheema, Jakob Korbelin, and Craig E. Brown

Collaterals and stroke reperfusion: too few leads to too much

Neuron - Cell Press

Patrick Reeson and Craig E. Brown

Sex and interferon gamma signaling regulate microglia migration in the adult mouse cortex in vivo

Proceedings of the National Academy of Sciences of the United States of America (PNAS)

Roobina Boghozian, Sorabh Sharma, Kamal Narayana, Manjinder Cheema, and Craig E. Brown

Optical opening of the blood-brain barrier for targeted and ultra-sparse viral infection of cells in mouse cortex

Cell Reports Methods: Cell Press

Patrick Reeson, Roobina Boghozian, Ana Paula Cota, and Craig E. Brown

Behavioral and Neural Activity-Dependent Recanalization of Plugged Capillaries in the Brain of Adult and Aged Mice

Frontiers in Cellular Neuroscience

Patrick Reeson, Ben Schager, Myrthe Van Sprengel and Craig E. Brown

Microvascular basis of cognitive impairment in type 1 diabetes

Journal of Pharmacology & Therapeutics

Sorabh Sharma and Craig E. Brown

Longitudinal functional imaging of VIP interneurons reveals sup-population specific effects of stroke that are rescued with chemogenetic therapy

Nature Communications

Mohamad Motaharinia, Kim Gerrow, Roobina Boghozian, Emily White, Sun-Eui Choi, Kerry R Delaney, and Craig E Brown

Invasion of phagocytic Galectin 3 expressing macrophages in the diabetic brain disrupts vascular repair

Science Advances

Eslam MF Mehina, Stephanie Taylor, Roobina Boghozian, Emily White, Sun Eui Choi, Manjinder S Cheema, Jakob Korbelin, and Craig E Brown

New Vistas in Stroke Treatment: Targeting the Endothelium to Restore Blood Flow

AHA/ASA Journals - Circulation Research

Patrick Reeson and Craig E. Brown

Susceptibility to capillary plugging can predict brain region specific vessel loss with aging

Journal of Cerebral Blood Flow & Metabolism

Ben Schager and Craig E Brown

Suppressing interferon-γ stimulates microglial responses and repair of microbleeds in the diabetic brain

The Journal of Neuroscience

Stephanie Taylor, Eslam Mehina, Emily White, Patrick Reeson, Kevin Yongblah, Kristian P Doyle, and Craig E Brown

VEGF signaling regulates the fate of obstructed capillaries in mouse cortex

eLife 

Patrick Reeson, Kevin Choi, and Craig E Brown

Optogenetic rewiring of thalamocortical circuits to restore function in the stroke injured brain

Nature Communications

Kelly A Tennant, Stephanie L Taylor, Emily R White, and Craig E Brown

Ultrastructural analysis of blood–brain barrier breakdown in the peri-infarct zone in young adult and aged mice

Journal of Cerebral Blood Flow & Metabolism

Patrick C Nahirney, Patrick Reeson, and Craig E Brown

bottom of page